UCSF Microbiology & Immunology

The Department of Microbiology & Immunology sponsors the following courses. To enroll in a course, contact your graduate school administrator. To audit a course, please contact the course director (see the UCSF campus directory for contact information).

GRADUATE SCHOOL
Micro 202. Microbial Pathogenesis.
James McKerrow, Eric Brown, Joanne Engel, Jeff Cox
The course will examine the interaction of selected bacterial, fungal, and parasitic pathogens with their eukaryotic hosts. Particular emphasis will be placed on the molecular mechanisms by which these invaders evade host defenses and cause disease.
Prerequisites: College course in microbiology recommended.
Lecture 2 hours. Seminar 1 hours.
Visit the Course Website

Micro 204. Molecular and Cellular Immunology.
Anthony DeFranco
Topics to be covered: hematopoiesis, structure and genetics of immunoglobulins, lymphocyte surface molecules, T cell receptors, signal transduction, antigen presentation, MHC restriction, tolerance, T cell effector mechanisms, lymphocynes, and autoimmunity.
Prerequisites: General knowledge of immunology.
Lecture 3 hours.
Visit the Course Website

Micro 208. Biology of Animal Virus Infection.
Donald Ganem
The nature of viruses: dynamics of virus-cell interaction with emphasis on animal virus systems, control of expression of virus-specific information in lytic and temperate infection, and role of viruses in malignant transformation of cells.
Prerequisites: General knowledge of nucleic acid structure and chemistry.
Lecture 3 hours.
Visit the Course Website

Micro 209. Advanced Topics in Immunology.
Staff
Small group tutorial in which topics and correlative reading will be selected for discussion with individual faculty members.
Prerequisites: Successful completion of Micro 204 or consent of course director.
Conference 2 hours.

MEDICAL SCHOOL
IDS 105. Infection, Immunity & Inflammation.
Warren Levinson, Anthony DeFranco
This course teaches the principles of basic microbiology and immunology needed for the practice of medicine, through lecture, lab, case studies and small group discussion.
Visit the Course Website

PHARMACY SCHOOL
Micro 120. Microbiology in Pharmacy.
Charles Hoover
Fundamentals of microbiology for pharmacy students with emphasis on mechanisms of disease production by bacteria, fungi, and viruses. Morphology, physiology, and immunology techniques used in laboratory diagnosis of selected bacterial diseases. Includes exercises in antibiotic susceptibility, disinfection, and sterility.
Prerequisites: Successful completion of all first-year required coursework.
Lecture 3 hours. Laboratory 3 hours.

Micro 121. Immunology.
Frances Brodsky
This course teaches the principles of basic immunology needed for the practice of pharmacy, as well as case studies covering immunology in the practice of clinical pharmacy.
Prerequisites: Microbiology 100A and 100B and consent of instructor.
Lecture 3 hours.

DENTAL SCHOOL
Micro 116. Microbiology & Immunology in Dentistry.
Carol Gross
Comprehensive presentation of microorganisms including bacteria, fungi, viruses; fundamentals of infection and resistance, immunology, disinfection, sterilization, and antimicrobial agents. Laboratory studies and demonstrations on indigenous oral flora and applications of microbiology to dentistry.
Lecture 4 hours. Laboratory 6 hours.

Chemokine Induced Lymphoid Neogenesis
The image shows the lymphoid structures formed in pancreatic islets of mice expressing the chemokine BLC (CXCL13) under control of the rat insulin promotor. BLC (in blue) is strongly expressed in the islet and causes attraction of naive B cells (IgD surface staining in green). In a B cell- and LTa1b2-dependent fashion, CD3+T cells (red) are recruited and form a T cell-rich zone. Transferred T and B lymphocytes (green intracellular staining, CFSE) efficiently enter these ectopic lymphoid structures and home into their respective compartments. For details, see Luther et al., 2000 (Immunity 12, 471-483). Image by Sanjiv Luther and Jason Cyster.