Silas, Sukrit, PhD

The Silas Lab is focused on addressing the global health crisis of antimicrobial resistance and expanding our understanding of the enormous genetic diversity of bacteriophages—viruses that infect and kill bacteria. By pinpointing common antivirus mechanisms in wild strains of pathogenic bacteria, the lab is painting a comprehensive picture of the entire defense architecture that phages encounter when infecting cells. Silas combines this information with AI-powered inferences to engineer phage cocktails that can be used as reliable therapeutic agents in our fight against drug-resistant bacteria.